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Beschreibung
This book provides an up-to-date overview of the architecture and biosynthesis of bacterial and archaeal cell walls, highlighting the evolution-based similarities in, but also the intriguing differences between the cell walls of Gram-negative bacteria, the Firmicutes and Actinobacteria, and the Archaea. The recent major advances in this field, which have brought to light many new structural and functional details, are presented and discussed. Over the past five years, a number of novel systems, e.g. for lipid, porin and lipopolysaccharide biosynthesis have been described. In addition, new structural achievements with periplasmic chaperones have been made, all of which have revealed amazing details on how bacterial cell walls are synthesized. These findings provide an essential basis for future research, e.g. the development of new antibiotics.
The book's content is the logical continuation of Volume 84 of SCBI (on Prokaryotic Cytoskeletons), and setsthe stage for upcoming volumes on Protein Complexes.
This book provides an up-to-date overview of the architecture and biosynthesis of bacterial and archaeal cell walls, highlighting the evolution-based similarities in, but also the intriguing differences between the cell walls of Gram-negative bacteria, the Firmicutes and Actinobacteria, and the Archaea. The recent major advances in this field, which have brought to light many new structural and functional details, are presented and discussed. Over the past five years, a number of novel systems, e.g. for lipid, porin and lipopolysaccharide biosynthesis have been described. In addition, new structural achievements with periplasmic chaperones have been made, all of which have revealed amazing details on how bacterial cell walls are synthesized. These findings provide an essential basis for future research, e.g. the development of new antibiotics.
The book's content is the logical continuation of Volume 84 of SCBI (on Prokaryotic Cytoskeletons), and setsthe stage for upcoming volumes on Protein Complexes.
Zusammenfassung

Offers a cutting-edge overview, comparing Gram+, Gram-, and Archaea cell walls

Provides novel insights into biosynthetic pathways of lipids, lipopolysaccharides, membrane proteins, transport, and assembly

Describes the molecular mechanisms and structural details of all currently known systems operating in prokaryotic cell walls

Summarizes the key lessons of each chapter with tutorials

Inhaltsverzeichnis
The bacterial cell wall and membrane - a treasure chest for antibiotic targets.- Lipopolysaccharide biosynthesis and transport to the outer membrane of Gram-negative bacteria.- Lipoproteins: structure, function, biosynthesis.- Outer membrane porins.- Peptidoglycan.- The Periplasmic Chaperones Skp and SurA.- Bacterial signal peptidases.- Carbohydrate Transport by Group Translocation: The Bacterial Phosphoenolpyruvate : Sugar Phosphotransferase System.- Secondary active transporters.- Respiratory membrane protein complexes convert chemical energy.- Inner membrane translocases and insertases.- The biosynthesis and structures of bacterial pili.- Cell Walls and Membranes of Actinobacteria.- Archaeal cell walls.
Details
Erscheinungsjahr: 2020
Fachbereich: Allgemeines
Genre: Biologie, Mathematik, Medizin, Naturwissenschaften, Technik
Rubrik: Naturwissenschaften & Technik
Thema: Lexika
Medium: Taschenbuch
Reihe: Subcellular Biochemistry
Inhalt: vi
501 S.
32 s/w Illustr.
51 farbige Illustr.
501 p. 83 illus.
51 illus. in color.
ISBN-13: 9783030187705
ISBN-10: 3030187705
Sprache: Englisch
Einband: Kartoniert / Broschiert
Autor: Kuhn, Andreas
Redaktion: Kuhn, Andreas
Herausgeber: Andreas Kuhn
Hersteller: Springer
Springer International Publishing AG
Subcellular Biochemistry
Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, D-69121 Heidelberg, juergen.hartmann@springer.com
Maße: 235 x 155 x 28 mm
Von/Mit: Andreas Kuhn
Erscheinungsdatum: 14.08.2020
Gewicht: 0,762 kg
Artikel-ID: 118834183