Alcohol abuse and alcoholism represents one of the major health, social, and economic issues facing not only America but much of the world. Problems with alcohol appear to be a common curse, afflicting almost all industrialized nations as well as the developing countries. at least 10 million people suffer the misuse. It is In the United States today of estimated that 205,000 individuals die prematurely each year from a variety ethanol-induced factors, including cirrhosis, cancer, heart disease, suicide, homi cide, and highway fatalities and other accidents. In purely economic terms, the alcohol-related cost to our society in 1975 is estimated at nearly [...] billion in lost production, medical expenses, motor vehicle accidents, fire losses, and the maintenance of social mechanisms to deal with these problems. But the economic impact pales in comparision with the psychological pain and anguish brought to alcoholics and their family and friends. The disease of alcoholism bears a close relation to the topic of our dedication, for it is equally insidious and sadistic, it destroys humanity and rational thought, and it brings terror, pain, and death.
Alcohol abuse and alcoholism represents one of the major health, social, and economic issues facing not only America but much of the world. Problems with alcohol appear to be a common curse, afflicting almost all industrialized nations as well as the developing countries. at least 10 million people suffer the misuse. It is In the United States today of estimated that 205,000 individuals die prematurely each year from a variety ethanol-induced factors, including cirrhosis, cancer, heart disease, suicide, homi cide, and highway fatalities and other accidents. In purely economic terms, the alcohol-related cost to our society in 1975 is estimated at nearly [...] billion in lost production, medical expenses, motor vehicle accidents, fire losses, and the maintenance of social mechanisms to deal with these problems. But the economic impact pales in comparision with the psychological pain and anguish brought to alcoholics and their family and friends. The disease of alcoholism bears a close relation to the topic of our dedication, for it is equally insidious and sadistic, it destroys humanity and rational thought, and it brings terror, pain, and death.
Inhaltsverzeichnis
VII. Ethanol and Electrolyte Metabolism.- 1 Water and Electrolyte Metabolism following Ethanol Intake and during Acute Withdrawal from Ethanol.- 2 Acid-Base Balance following Ethanol Intake and during Acute Withdrawal from Ethanol.- 3 Metabolism of Calcium and Magnesium during Ethanol Intoxication and Withdrawal.- VIII. Influence of Ethanol on Biological Membranes.- 4 Effects of Ethanol on Membrane Transport.- 5 Changes in the Activity of Na+,K+-ATPase during Acute and Chronic Administration of Ethanol.- 6 Biochemical and Biophysical Approaches in the Study of Ethanol- Membrane Interaction.- 7 Ethanol and the Blood-Brain Barrier.- IX. Interaction of Ethanol with Hormonal Functions.- 8 Effects of Acute and Chronic Administration of Ethanol on Cyclic Nucleotides and Related Systems.- 9 Interactions of Thyrotropin-Releasing Hormone and Somatostatin with Ethanol and Other Sedative/Hypnotics.- 10 Ethanol and Endocrine Function.- X. Interaction of Ethanol with Neurotransmitters.- 11 Alterations in Neurotransmitter Function after Acute and Chronic Treatment with Ethanol.- 12 Comparison between the Effects of Ethanol and Those of Opioid Drugs on the Metabolism of Biogenic Amines.- 13 Genetics of Ethanol Preference: Role of Neurotransmitters.- 14 Effects of Ethanol on the Cholinergic System.- XI. Ethanol and Neuronal Electrophysiology.- 15 Effects of Ethanol on Nerve Impulse Activity.- 16 Tolerance to a Specific Synaptic Effect of Ethanol in Aplysia.- XII. Interaction of Ethanol with Drugs.- 17 Interaction of Ethanol with Other Drugs.- 18 Biochemical Pharmacology of Pyrazoles.- 19 Biochemical Pharmacology of Disulfiram.- 20 Amethystic Agents: Reversal of Acute Ethanol Intoxication in Humans.- 21 Drug Therapy of the Alcohol Withdrawal Syndrome.- XIII. Physiology, Behavior, and Animal Models of Alcohol Dependence.- 22 Ethanol-Induced Changes in Body Temperature and Their Neurochemical Consequences.- 23 Interrelationship between Ethanol Consumption and Circadian Rhythm.- 24 Pharmacologic and Electrophysiologic Effects of Ethanol in Relation to Sleep.- 25 Clinical Pharmacology of the Fetal Alcohol Syndrome.- 26 Behavioral Manifestations of Ethanol Intoxication and Physical Dependence.- 27 A Critique of Animal Analogues of Alcoholism.
