Jim E Riviere: Comparative Pharmacokinetics

Cover: 9780813829937 | Comparative Pharmacokinetics | Principles, Techniques and Applications

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Beschreibung

Now in a revised edition, Comparative Pharmacokinetics: Principles, Techniques, and Applications presents the principles and techniques of comparative and veterinary pharmacokinetics in a detailed yet practical manner. Developed as a tool for ensuring that pharmacokinetics studies are properly designed and correctly interpreted, the book provides complete coverage of the conceptual basis of pharmacokinetics as used for quantifying biological processes from the perspectives of physiology and medicine. New chapters have been added on quantitative structure permeability relationships and bioequivalence, and a number of existing chapters have been significantly revised and expanded to provide a current resource for veterinary and comparative pharmacokinetics.

Über den Autor

Jim Riviere, DVM, PhD, DSc (hon), ATS, is the Burroughs Wellcome Fund Distinguished Professor of Pharmacology, Alumni Distinguished Graduate Professor, and Director of the Center for Chemical Toxicology Research and Pharmacokinetics at North Carolina State University, and Editor of the Journal of Veterinary Pharmacology and Therapeutics.

Inhaltsverzeichnis

Coauthors.

Preface.

1 Introduction.

2 Principles of Drug Movement in the Body.

3 Quantitative Structure-Permeability Relationships (Xin-Rui Xia).

4 Absorption.

5 Distribution (with Jennifer Buur).

6 Renal Elimination.

7 Hepatic Biotransformation and Biliary Excretion (Ronald Baynes).

8 Compartmental Models.

9 Noncompartmental Models.

10 Nonlinear Models.

11 Physiological Models (Teresa Leavens).

12 Dosage Regimens.

13 Simultaneous Pharmacokinetic-Pharmacodynamic Modeling (Pierre-Louis Toutain).

14 Study Design and Data Analysis. (Jason Chittenden).

15 Bioequivalence Studies (Marilyn Martinez).

16 Population Pharmacokinetic Models (Jason Chittenden).

17 Dosage Adjustments in Disease States (Jennifer Davis).

18 Interspecies Extrapolations.

19 Tissue Residues and Withdrawal Times (Sharon Mason).

Index.

Details

Erscheinungsjahr:	2011
Fachbereich:	Tiermedizin
Genre:	Importe , Medizin
Rubrik:	Wissenschaften
Medium:	Buch
Inhalt:	376 S.
ISBN-13:	9780813829937
ISBN-10:	0813829933
Sprache:	Englisch
Einband:	Gebunden
Autor:	Riviere, Jim E
Redaktion:	Riviere, Jim E
Auflage:	2nd Secondtion edition
Hersteller:	Wiley John Wiley & Sons
Verantwortliche Person für die EU:	Wiley-VCH GmbH, Boschstr. 12, D-69469 Weinheim, product-safety@wiley.com
Maße:	261 x 182 x 28 mm
Von/Mit:	Jim E Riviere
Erscheinungsdatum:	12.04.2011
Gewicht:	1,026 kg

Artikel-ID: 106571802