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Jixian Wang is a principal statistician at Celgene International, Switzerland. He worked on drug development for 14 years at GSK and Novartis Pharma and was an academic researcher at Edinburgh University and Dundee University, where he is still an honorary research fellow. His research interests include statistical methodology and its applications to real problems in pharmaceuticals, including exposure-safety, PKPD modeling, treatment/dose selection, health economics, benefit-risk and health technology assessments, and optimal trial design.
Introduction. Basic exposure and exposure-response models. Dose-exposure and exposure-response models for longitudinal data. Sequential and simultaneous exposure-response modeling. Exposure-risk modeling for time-to-event data. Modeling dynamic exposure-response relationships. Bayesian modeling and model-based decision analysis. Confounding bias and causal inference in exposure-response modeling. Dose-response relationship, dose determination, and adjustment. Implementation using software. Appendix. Bibliography. Index.
| Erscheinungsjahr: | 2020 |
|---|---|
| Fachbereich: | Wahrscheinlichkeitstheorie |
| Genre: | Importe, Mathematik |
| Rubrik: | Naturwissenschaften & Technik |
| Medium: | Taschenbuch |
| ISBN-13: | 9780367738044 |
| ISBN-10: | 036773804X |
| Sprache: | Englisch |
| Einband: | Kartoniert / Broschiert |
| Autor: | Wang, Jixian |
| Hersteller: | CRC Press |
| Verantwortliche Person für die EU: | Libri GmbH, Europaallee 1, D-36244 Bad Hersfeld, gpsr@libri.de |
| Maße: | 231 x 155 x 25 mm |
| Von/Mit: | Jixian Wang |
| Erscheinungsdatum: | 18.12.2020 |
| Gewicht: | 0,54 kg |
Jixian Wang is a principal statistician at Celgene International, Switzerland. He worked on drug development for 14 years at GSK and Novartis Pharma and was an academic researcher at Edinburgh University and Dundee University, where he is still an honorary research fellow. His research interests include statistical methodology and its applications to real problems in pharmaceuticals, including exposure-safety, PKPD modeling, treatment/dose selection, health economics, benefit-risk and health technology assessments, and optimal trial design.
Introduction. Basic exposure and exposure-response models. Dose-exposure and exposure-response models for longitudinal data. Sequential and simultaneous exposure-response modeling. Exposure-risk modeling for time-to-event data. Modeling dynamic exposure-response relationships. Bayesian modeling and model-based decision analysis. Confounding bias and causal inference in exposure-response modeling. Dose-response relationship, dose determination, and adjustment. Implementation using software. Appendix. Bibliography. Index.
| Erscheinungsjahr: | 2020 |
|---|---|
| Fachbereich: | Wahrscheinlichkeitstheorie |
| Genre: | Importe, Mathematik |
| Rubrik: | Naturwissenschaften & Technik |
| Medium: | Taschenbuch |
| ISBN-13: | 9780367738044 |
| ISBN-10: | 036773804X |
| Sprache: | Englisch |
| Einband: | Kartoniert / Broschiert |
| Autor: | Wang, Jixian |
| Hersteller: | CRC Press |
| Verantwortliche Person für die EU: | Libri GmbH, Europaallee 1, D-36244 Bad Hersfeld, gpsr@libri.de |
| Maße: | 231 x 155 x 25 mm |
| Von/Mit: | Jixian Wang |
| Erscheinungsdatum: | 18.12.2020 |
| Gewicht: | 0,54 kg |
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