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Beschreibung
The most engaging and accessible account of cancer biology which clearly links our understanding of cancer with the development of new therapeutics.

Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students.

Key features
- Describes the theoretical basis of cancer biology and shows how this theory is applied to develop new cancer therapies, giving students a clear appreciation of how theoretical knowledge can be translated into therapeutic strategies
- Draws on the latest research in cancer biology
- Features a variety of learning features to help students engage with the concepts presented: 'Pause and think'; 'How do we know that?'; 'In the clinic'; self-tests; and activities

New to this edition
- New themes that weave throughout the book, such as the two-way interactions between the microenvironment and the tumour, systemic effects of cancer, and the role of plasticity and heterogeneity in cancer evolution
- Expanded coverage of cancer genomics, including single cell genomics and spatial transcriptomics, highlighted in the concluding chapter
- A new feature called 'In the clinic' that highlights current or potential applications of cancer biology to clinical practice
- Updates on newly approved cancer therapeutics
- Includes additional primary data from the literature and key references to provide a resource of up-to-date experimental evidence
- Expanded artwork programme and new 'figure sequences' (in the enhanced e-book) to help readers understand molecular pathways over time

Digital formats and resources
The 6th edition is available for students and institutions to purchase in a variety of formats: the e-book and Science Trove offer a mobile experience and convenient access along with multiple choice questions, audio clips, functionality tools, navigation features and links that offer extra learning support.

For more information about e-books, please visit [...]
The most engaging and accessible account of cancer biology which clearly links our understanding of cancer with the development of new therapeutics.

Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students.

Key features
- Describes the theoretical basis of cancer biology and shows how this theory is applied to develop new cancer therapies, giving students a clear appreciation of how theoretical knowledge can be translated into therapeutic strategies
- Draws on the latest research in cancer biology
- Features a variety of learning features to help students engage with the concepts presented: 'Pause and think'; 'How do we know that?'; 'In the clinic'; self-tests; and activities

New to this edition
- New themes that weave throughout the book, such as the two-way interactions between the microenvironment and the tumour, systemic effects of cancer, and the role of plasticity and heterogeneity in cancer evolution
- Expanded coverage of cancer genomics, including single cell genomics and spatial transcriptomics, highlighted in the concluding chapter
- A new feature called 'In the clinic' that highlights current or potential applications of cancer biology to clinical practice
- Updates on newly approved cancer therapeutics
- Includes additional primary data from the literature and key references to provide a resource of up-to-date experimental evidence
- Expanded artwork programme and new 'figure sequences' (in the enhanced e-book) to help readers understand molecular pathways over time

Digital formats and resources
The 6th edition is available for students and institutions to purchase in a variety of formats: the e-book and Science Trove offer a mobile experience and convenient access along with multiple choice questions, audio clips, functionality tools, navigation features and links that offer extra learning support.

For more information about e-books, please visit [...]
Über den Autor
Professor Lauren Pecorino obtained her PhD in Cell and Developmental Biology at the State University of New York at Stony Brook, USA. She then moved to London to carry out a post-doctoral tenure at the Ludwig Institute for Cancer Research where she studied the phenomenon of limb regeneration. Here she used a technique called biolistics, using a 'gene gun' to shoot gold bullets coated with DNA to introduce genes into the regenerating limbs of live newts. Since 1996, Lauren has been a member of academic staff at the University of Greenwich, where she developed her interest in teaching Cancer Biology. She is a Fellow of the Royal Society of Medicine, Fellow of the Royal Society of Biology, and Senior Fellow of the Higher Education Academy.
Inhaltsverzeichnis
  • 1: Introduction

  • 2: The transformable cancer genome: mutations versus repair

  • 3: Regulation of gene expression

  • 4: Growth factor signaling and oncogenes

  • 5: The cell cycle

  • 6: Tumour suppressor genes

  • 7: Apoptosis

  • 8: Cancer stem cells, lineage plasticity and disrupted differentiation: focus on colon cancer and leukemias

  • 9: Metastasis

  • 10: Angiogenesis

  • 11: Reprogrammed metabolism and diet

  • 12: Tumour immunology and immunotherapy

  • 13: Inflammation, infection, and the microbiome

  • 14: Cancer genomics and other methods for research and clinical development

Details
Erscheinungsjahr: 2026
Fachbereich: Chirurgie
Genre: Importe, Medizin
Rubrik: Wissenschaften
Medium: Taschenbuch
ISBN-13: 9780198899693
ISBN-10: 0198899696
Sprache: Englisch
Einband: Kartoniert / Broschiert
Autor: Pecorino, Lauren
Auflage: 6. Auflage
Hersteller: Oxford University Press
Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, D-36244 Bad Hersfeld, gpsr@libri.de
Maße: 246 x 192 x 27 mm
Von/Mit: Lauren Pecorino
Erscheinungsdatum: 14.01.2026
Gewicht: 0,996 kg
Artikel-ID: 134564770

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