Zum Hauptinhalt springen Zur Suche springen Zur Hauptnavigation springen
Beschreibung
The synucleinopathy sporadic Parkinson¿s disease (sPD) is the second most frequent degenerative disorder of the human nervous system after Alzheimer¿s disease. The propensity for developing sPD exists in all ethnic groups worldwide, and the prevalence of the disorder increases considerably with age, thereby imposing an enormous social and economic burden on societies with increased life expectancy. The sPD-associated pathological process is progressive, does not go into remission, and can take decades to reach its culmination if it is not be terminated prematurely by death owing to other causes.

Against the background of the normal morphology and anatomy, the authors analyze the pathoanatomy of sPD in the nervous system at various neuropathological stages and summarize the potential functional consequences of the lesions.
The synucleinopathy sporadic Parkinson¿s disease (sPD) is the second most frequent degenerative disorder of the human nervous system after Alzheimer¿s disease. The propensity for developing sPD exists in all ethnic groups worldwide, and the prevalence of the disorder increases considerably with age, thereby imposing an enormous social and economic burden on societies with increased life expectancy. The sPD-associated pathological process is progressive, does not go into remission, and can take decades to reach its culmination if it is not be terminated prematurely by death owing to other causes.

Against the background of the normal morphology and anatomy, the authors analyze the pathoanatomy of sPD in the nervous system at various neuropathological stages and summarize the potential functional consequences of the lesions.
Inhaltsverzeichnis
Prologue.- Morphology of Lewy Pathology.- The Evolving Distribution Pattern of Lewy Pathology Associated with sPD Renders Neuropathological Staging Possible.- Stage 1.- Stage 2.- Stage 3.- Stage 4.- Stages 5 and 6.- The Progression of the Cortical Lesions Mimics the Pattern of Myelination in Reverse Order.- The Staging Hypothesis: Assumptions, Challenges, Potential.
Details
Erscheinungsjahr: 2008
Fachbereich: Therapie
Genre: Mathematik, Medizin, Naturwissenschaften, Technik
Rubrik: Wissenschaften
Medium: Taschenbuch
Reihe: Advances in Anatomy, Embryology and Cell Biology
Inhalt: vii
119 S.
29 farbige Illustr.
119 p. 29 illus. in color.
ISBN-13: 9783540798491
ISBN-10: 3540798498
Sprache: Englisch
Herstellernummer: 12073405
Einband: Kartoniert / Broschiert
Autor: Braak, Heiko
Del Tredici, Kelly
Hersteller: Springer
Springer-Verlag GmbH
Advances in Anatomy, Embryology and Cell Biology
Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, D-69121 Heidelberg, juergen.hartmann@springer.com
Maße: 235 x 155 x 8 mm
Von/Mit: Heiko Braak (u. a.)
Erscheinungsdatum: 03.12.2008
Gewicht: 0,207 kg
Artikel-ID: 101791910