State of the art reviews by experts in the fields of neuroscience, immunology, microbiology/infectious diseases and pharmacology

Looks at the convergence of the immune system and the loss of neurons in diseases such as Alzheimer's, Parkinson's, Multiple Sclerosis and Huntington's

Contains a section on novel approaches to therapy

Includes supplementary material: [...]

The Blood Brain Barrier.- Immune Cell Trafficking in the Central Nervous System.- General Physiology and Pathophysiology of Microglia


Inflammation and the Pathophysiology of Astrocytes in Neurodegenerative Diseases.- Oxidative stress, neuroinflammation, and neurodegeneration.- Peripheral Neuroimmune Interactions and Neuropathic Pain.- Innate and Adaptive Immune-Mediated Neuroinflammation and Neurodegeneration in Parkinson's Disease.- Multiple sclerosis: impact on functioning of the blood-brain barrier.- Neuroinflammation in Alzheimer's disease.- Neuroinflammation in Huntington's Disease.- Neuroinflammation and immune regulation in ischemic stroke: identification of new pharmacological targets.- HIV/NeuroAIDS.- Herpes Simplex Virus Infections Of The Central Nervous System.- Congenital Cytomegalovirus Disease.- Japanese Encephalitis: A Tale of Inflammation and Degeneration in the Central Nervous System.- The biology and clinical consequence of infection with the human polyomavirusJCV.- Role of Retrovirus-Induced Transactivator Proteins in Neuroinflammatory Disease.- Immunopathogenesis of bacterial meningitis.- Cerebral Malaria.- HIV and Cocaine Interplay in HIV-associated Neurocognitive Disorders.- Methamphetamine Neurotoxicity and Neuroinflammatory Processes.- Drugs of Abuse and NeuroAIDS: Opiates.- Cannabinoids.- Alcohol and Neurodegeneration.- Cell-Based Drug Delivery for Improving Antiretroviral Therapeutic Outcomes.- Immunomodulatory Therapeutics for Neurodegenerative Diseases.- Therapeutic Potential Of Cannabinoids