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This volume explores an array of diseases in humans associated with L1 retrotransposon movement within the human genome, including some cancers such as colon cancer and neuropsychiatric disorders such as schizophrenia.
The chapters explore the diversity of retrotransposons, their different biological mechanisms, the role of L1 in their movement, and their contribution to human diseases. This book posits that somatic events caused by retrotransposons have implications for mosaicism and are often associated with cancers. Germline events are common, occur quite early in development, and are a cause of single gene diseases. All in all, the authors implicate L1 retrotransposons as major sources of human diversity and advocate for their continued study.
This volume explores an array of diseases in humans associated with L1 retrotransposon movement within the human genome, including some cancers such as colon cancer and neuropsychiatric disorders such as schizophrenia.
The chapters explore the diversity of retrotransposons, their different biological mechanisms, the role of L1 in their movement, and their contribution to human diseases. This book posits that somatic events caused by retrotransposons have implications for mosaicism and are often associated with cancers. Germline events are common, occur quite early in development, and are a cause of single gene diseases. All in all, the authors implicate L1 retrotransposons as major sources of human diversity and advocate for their continued study.
| Erscheinungsjahr: | 2022 |
|---|---|
| Fachbereich: | Gentechnologie |
| Genre: | Biologie, Importe |
| Rubrik: | Naturwissenschaften & Technik |
| Medium: | Buch |
| Inhalt: | Gebunden |
| ISBN-13: | 9789811249211 |
| ISBN-10: | 9811249210 |
| Sprache: | Englisch |
| Einband: | Gebunden |
| Autor: | Abram Gabriel |
| Redaktion: | Abram Gabriel |
| Hersteller: | World Scientific |
| Verantwortliche Person für die EU: | Libri GmbH, Europaallee 1, D-36244 Bad Hersfeld, gpsr@libri.de |
| Maße: | 235 x 157 x 19 mm |
| Von/Mit: | Abram Gabriel |
| Erscheinungsdatum: | 05.08.2022 |
| Gewicht: | 0,532 kg |
| Erscheinungsjahr: | 2022 |
|---|---|
| Fachbereich: | Gentechnologie |
| Genre: | Biologie, Importe |
| Rubrik: | Naturwissenschaften & Technik |
| Medium: | Buch |
| Inhalt: | Gebunden |
| ISBN-13: | 9789811249211 |
| ISBN-10: | 9811249210 |
| Sprache: | Englisch |
| Einband: | Gebunden |
| Autor: | Abram Gabriel |
| Redaktion: | Abram Gabriel |
| Hersteller: | World Scientific |
| Verantwortliche Person für die EU: | Libri GmbH, Europaallee 1, D-36244 Bad Hersfeld, gpsr@libri.de |
| Maße: | 235 x 157 x 19 mm |
| Von/Mit: | Abram Gabriel |
| Erscheinungsdatum: | 05.08.2022 |
| Gewicht: | 0,532 kg |
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