Tomie dePaola was born in Meriden, Connecticut, in 1934, to a family of Irish and Italian background. His determination to create books for children led to a BFA from Pratt Institute in Brooklyn, New York, and an MFA from the California College of Arts & Crafts in Oakland, California.

His particular way with color, line, detail, and design have earned him many of the most prestigious awards in his field, among them a Caldecott Honor Award for Strega Nona, the Smithsonian Medal, the Kerlan Award from the University of Minnesota for his "singular attainment in children's literature," the Catholic Library Association's Regina Medal for his "continued distinguished contribution," and the University of Southern Mississippi Medallion. He was also the 1990 United States nominee for the Hans Christian Andersen Medal for illustration, and received the Laura Ingalls Wilder Award for lifetime contribution to children's literature in 2011.

DePaola published over 250 children's books in 15 different countries. Among his most well-known titles are the Strega Nona series, 26 Fairmount Avenue, and The Legend of the Indian Paintbrush.

Tomie dePaola lived in New Hampshire and worked in a 200-year-old renovated barn. He died on March 30, 2020.